European partnership for pandemic preparedness

Open call 




The scope of the partnership should encompass:

  • basic research to accelerate the acquisition of knowledge on the biology of pathogens with epidemic or pandemic potential, their transmission and interaction with humans, animals and plants, in particular in view of emerging threats to human health. The initial focus should be on pathogens with high epidemic or pandemic potential for the EU, such as those included in the list of priority diseases of the World Health Organization (WHO), with particular attention to those meeting the criteria identified by HERA;
  • preclinical research aimed at better understanding of human diseases caused by pathogens with epidemic or pandemic potential and testing of related medical countermeasures;
  • clinical research to support the generation of novel solutions, in particular the development (phase I to phase III) of medical countermeasures, e.g. vaccines, diagnostics, therapeutics and digital solutions, to prevent or mitigate outbreaks from pathogens with epidemic or pandemic potential, in line with the mission of HERA and the ACT EU initiative;
  • a key feature should be the consolidation and further development of an ever-warm network of clinical trial sites applying the same quality standards and ensuring a baseline of continuous clinical trial activity across a wide and diverse range of clinical trial sites, to allow for a rapid clinical trial response in case of an epidemic or pandemic. This includes the development of criteria for a clinical trial site to be considered as ever-warm;
  • the development, testing and validation of new methods and tools, including those based on artificial intelligence and computer modelling, to improve surveillance and diagnosis and control of the spread of pathogens with epidemic or pandemic potential;
  • the conduct of public health and social sciences and humanities (SSH) research for the development and robust evaluation of appropriate non-pharmaceutical interventions/public health and social measures and effective communication strategies at all phases of a public health emergency;
  • the consolidation and/or development of infrastructures, platforms and networks necessary for fast and timely start of the response research, capitalising on previous investments and existing infrastructures supporting collaboration, trans-boundary access and provision of services, such as provided by ISIDORe or ECRIN.
  • capacity building through networking and training of researchers, to share knowledge and good practices also with EU and national entities, policymakers and funders.

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