OPERAM

Optimising Therapy to prevent avoidable hospital admissions in the multimorbid elderly

Project duration: 01.05. 2015 - 30.04. 2020     terminated

 

OPERAM was supported by the European Commision's Horizon 2020 programme under the grant agreement No 634238,
and by the Swiss State Secretariat for Education, Research and Innovation (SERI) under contract number 15.0137.

 

Coordinator

University of Bern, CH
Department of General Internal Medicine, Inselspital,
Bern University Hospital and Berner Institut für Hausarztmedizin (BIHAM)
Prof. Dr. Nicolas Rodondi

Partners

Université catholique de Louvain, BE
Clinical Pharmacy Research Group of the Louvain Drug Research Institute (LDRI/CLIP)
Prof. Dr. Anne Spinewine

Cliniques Universitaires Saint Luc, BE
Prof. Dr. Olivia Dalleur             

Utrecht University, NL
Department of Information and Computing Sciences
Dr. Marco Spruit         

Cork University Hospital, IE
Department of Medicine, Schools of Medicine and Pharmacy
Department of Epidemiology and Public Health
University College Cork and Department of Geriatric Medicine
Prof. Dr. Denis O'Mahony

Universität Basel, CH
Institute of Pharmaceutical Medicine (ECPM), a member of the Department of Public Health at the Medical Faculty
Prof. Dr. Matthias Schwenkglenks

tp21 GmbH, DE
Dr. Petra Zalud

University of Ioannina, GR
Department of Primary Education, School of Education of the University of Ioannina
Prof. Dr. Dimitris Mavridis        

University Medical Center Utrecht, NL
Department of Geriatric Medicine and Expertise Centre Pharmacotherapy in Old Persons
Dr. Wilma Knol

Università degli Studi 'G. d'Annunzio' Chieti e Pescara, IT
Department of Medical, Oral and Biotechnological Sciences
Prof. Dr. Marcello Di Nisio

Objectives

The overall aim of OPERAM (OPtimising thERapy to prevent Avoidable hospital admissions in the Multimorbid elderly) is to optimise existing pharmacological and non-pharmacological therapy primarily in order to reduce avoidable hospital admissions among the elderly population aged ≥75 years with multimorbidity.

Specifically, the OPERAM consortium aims at:

• • Creating new evidence to prevent avoidable hospital admissions through optimising pharmacotherapy in the multimorbid elderly by performing a multi-centre cluster randomised clinical trial (RCT) to assess the impact of a structured medication review
  • Obtaining evidence-based data comparing pharmacological and non-pharmacological interventions to prevent common causes of avoidable hospital admissions in the elderly with multimorbidity, and rank these interventions according to their effectiveness and safety using network meta-analyses (NMA)
  • Identify the most cost-effective pharmacological and non-pharmacological interventions to prevent avoidable hospital admissions in the multimorbid elderly

 

Final Project Executive Summary and Results    

 

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